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Background—Infections skin diseases caused by Staphylococcus aureus (S.aureus) and Staphylococcus epidermidis (S.epidermidis) are still increasing worldwide under the management of current infection control methods.Novel methods for disinfecting above mentioned drug-resistant strains would be useful.We tested the effectiveness of non-theraml atmospheric pressure plasma jets at killing S.aureus and S.epidermidis in vitro settings experimentally.