Objective: Our aim was to evaluate the quality of life (QoL) in patients with ameloblastoma who had been treated by immediate mandibular reconstruction with a fibular free flap, and to analyse the association between QoL and their sociocultural and medical characteristics Methods: We assessed the QoL outcomes of 33/45 patients using the University of Washington quality of life (UWQoL) questionnaire and the 14-item Oral Health Impact Profile (OHIP-14).Thirty-three of the 45 questionnaires were returned (73％).