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Objective Objective: Genetic biomarkers of lung cancer(LC)susceptibility may provide a basis for treatment and prevention.This study analyzed an association between SNPs in the complementary region of the 3′-UTR of microRNAs of the gene RIPK1(receptorinteracting serine/threonine-protein kinase 1)and LC among an adult Han Chinese population aged younger than 60 years.Also explored was the effect of regulation of RIPK1 gene via rs17548629 and microRNA-1197 on the occurrence of LC.