早发性肝癌HBV高频整合位点的发现及功能研究

来源 :2016第九届世界癌症大会 | 被引量 : 0次 | 上传用户：lyh327

【摘要】

：

HBV感染是肝细胞癌(HCC)发生的重要原因.但长期以来有两个现象令人困惑：同样是感染乙肝病毒,20％左右的人发病年龄低于30岁,40％以上的HBV携带者发病年龄大于70岁或终生不发生HCC.其次,HCC发病具有明显的家族聚集性,在同一家庭中HCC发病年龄常常比较接近.较之晚发肝癌,早发肝癌起病更为隐匿,不容易发现,而且恶性程度更高,预后更差,研究早发肝癌的发病机制对于预防和治疗早发肝癌意义重大.

【作者】

：

颜宏利

【机构】

：

中国人民解放军附属长海医院实验诊断科中国

【出处】

：

2016第九届世界癌症大会

【发表日期】

：

2016年7期

下载到本地 , 更方便阅读

下载此文赞助VIP

声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架

论文部分内容阅读

其他文献

Laparoscopic Nerve-Sparing Radical Hysterectomy for Cervical Carcinoma:Emphasis on Nerve Content in

Objective: To evaluate the histopathology of autonomic nerve removal within the cardinal ligaments (CLs),patients postoperative urinary function,and the feasibility and safety of laparoscopic nerve-sp

会议

Genetic Analysis Results of Ovarian Mature Cystic Teratomas in Taiwan Disagree with the Previous Ori

The most accepted theory regarding mature cystic teratomas of the ovary is that they are of parthenogenetic origin from oocyte after the completion of first division.

会议

Parity Correlates with the Timing of Developing Endometrial Cancer, But Not Subtype of Endometrial C

Parity is one of well-known risk factors of endometrial cancer,but it is less clear whether parity is associated with the timing of developing endometrial cancer,and with the incidence of subtype of e

会议

A New Sonographic Morphology Score for the Diagnosis of Ovarian Tumors

Objective: The aim of this study was to explore the efficacy of a new sonographic morphology score (SMS) to differentiate malignant from benign ovarian tumors.

会议

The Impact of PET Imaging and Ga-68-labeled Peptides in Oncological Patients

New combined PET-CT and PET-MRI scanners revolutionized the oncological diagnostics and therapy monitoring due to the combined assessment of anatomical and functional changes in tumors.

会议

Multi-wavelength and Multi-spectral Modulation Strategies for Highly Sensitive Cancer Imaging Using

This keynote talk will be divided into three novel cancer imaging topics.First,I will discuss Wavelength Modulated Differential Photoacoustic Spectroscopy (WM-DPAS) for noninvasive early cancer detect

会议

Pathological Tissue Permittivity Distribution Difference Imaging: Near-field Microwave Tomographic I

Different breast tissue with different dielectric properties,especially for the Permittivity of cancerous tissue is much higher than that of normal tissue.

会议

Factors Associated with the Quality of Sexual Life in Patients After Allo-hematopoietic Stem Cell Tr

The major purpose of this descriptive and correlational study was to investigate the quality of sexual life and associated factors for patients who had received allogeneic stem cell transplantation.

会议

Abnormal Savda Munziq (ASMq) and Cisplatin Synergistically Regulate the Expression of Bcl-2, Survivi

The aim of our study was to evaluate the anti-tumor effects of total phenolics derived from abnormal savda munziq (ASMq) in combination with cisplatin on HeLa cervical cancer cell line..We detected th

会议

An Iridium(Ⅲ)-based Inhibitor of BRD4 with Potent Anticancer Activity in vivo

Bromodomain-containing protein 4 (BRD4) has recently emerged as an attractive epigenetic target for anticancer therapy.In this study,an iridium(Ⅲ) complex is reported as the first metal-based inhibito

会议

早发性肝癌HBV高频整合位点的发现及功能研究

与本文相关的学术论文