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目的:研究三七粉对腹部创伤大鼠凝血异常的改善作用。方法:通过盲肠结扎穿刺(CLP)法建立大鼠腹部创伤模型,分为正常对照组、假手术组、模型组、三七粉组,测定其活化部分凝血酶时间(APTT)、凝血酶原时间(PT)、凝血酶时间(TT)。结果:与假手术组比较,模型组凝血指标明显升高,三七粉组凝血指标升高程度比模型组低。结论:三七粉对腹部创伤大鼠凝血功能异常有改善作用。
Objective: To study the effect of Panax notoginseng on coagulation abnormalities in abdominal trauma rats. Methods: The model of abdominal trauma was established by cecal ligation and puncture (CLP). The model was divided into normal control group, sham operation group, model group and Sanqi powder group. The activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT). Results: Compared with the sham-operated group, the coagulation index of the model group was significantly increased. The coagulation index of the Panax notoginseng powder group was lower than that of the model group. Conclusion: Panax notoginseng can improve coagulation dysfunction in abdominal trauma rats.