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目的分析研究早产有关的危险因素及早产儿发病及死亡的相关因素。方法对2009年1月1日-2010年12月31日住院分娩237例早产患者的临床资料进行回顾性分析,并随机抽取足月分娩的237例进行相关对照。比较孕28~31+6、32~34+6、35~36+6周和足月孕龄新生儿窒息和新生儿死亡的差异。结果不明原因早产,胎膜早破,重度子痫前期,多胎妊娠,产前出血为早产原因的前5位;早产还与孕期母亲未做产前检查相关。早产与对照组新生儿窒息和死亡发生率差异有统计学意义(P<0.01)。结论早产病因复杂,减少早产的发生率关键是重视围产期保健,积极防治妊娠并发症。早产是围产儿发病和死亡的主要原因,重视早产的临床相关因素并采取相应措施,可降低围生儿并发症及死亡率。
Objective To analyze the risk factors related to prematurity and the related factors of morbidity and mortality in premature infants. Methods A retrospective analysis was performed on clinical data of 237 cases of preterm labor admitted to hospital from January 1, 2009 to December 31, 2010. 237 cases of full-term labor were randomly selected for related control. More pregnant 28 ~ 31 +6, 32 ~ 34 +6, 35 ~ 36 + 6 weeks and full-term gestational age neonatal asphyxia and neonatal mortality differences. Results unexplained premature delivery, premature rupture of membranes, severe preeclampsia, multiple pregnancies, prenatal bleeding is the top 5 causes of preterm birth; preterm labor and prenatal mothers did not do prenatal care. The incidence of neonatal asphyxia and death in preterm and control groups was significantly different (P <0.01). Conclusion The etiology of preterm birth is complex and the key to reducing the incidence of preterm birth is to pay attention to perinatal care and to prevent and treat pregnant complications. Preterm birth is the main cause of perinatal morbidity and mortality, attention to premature clinical factors and take appropriate measures to reduce perinatal complications and mortality.