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本文对几种不同结构类型的催化裂化金属钝化剂用小鼠进行了毒性试验,并分析其毒性与化学结构的关系.结果表明LMP-4型钝化剂毒性较小,LD50为28400mg/kg,LMP-2钝化剂毒性较大,LD50为1971.9mg/kg,从化学结构分析可以看出,含硫磷配位基团的钝化剂毒性最大,含硫配位基团的毒性次之,含氧配位基团的最小,说明金属钝化剂的毒性与化学结构有密切关系。
In this paper, several different types of catalytic cracking metal deactivators were used in mice toxicity test and analysis of its toxicity and chemical structure. The results showed that LMP-4 passivator was less toxic, LD50 was 28400mg / kg, LMP-2 passivator was more toxic and LD50 was 1971.9mg / kg. It can be seen from chemical structure analysis that the content of phosphorus The passivation of the group is the most toxic, followed by the toxicity of the sulfur-containing coordination group, the smallest oxygen-containing coordination group, indicating that the toxicity of the metal deactivator is closely related to the chemical structure.