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高血压病是危害老年人健康的多发病,治疗较为困难。研究老年高血压病特点及药物治疗的报导日益增多。本文主要对老年降压药物应用和常为首选的噻嗪类(Tbiazideg),以及近年临床试用的异搏定(Verapamil)与心得舒(Alprenolol)的疗效观察概述如下。一、老年高血压病的特点据调查人群中高血压的发病率,常随年龄的增长而增高(但巴西土著印第安族,血压并不随年龄增长而递增,可能与该族食盐含量低有关)。Sleigh七认为老年主动脉硬化斑块逐渐形成,并扩延至颈动脉窦,继之被胶元纤维代替,使其中压力感受器敏感性降低,导致迷走神经紧张性减弱,交感神经
Hypertension is endangering the health of the elderly and is more difficult to treat. There are increasing reports about the characteristics of elderly hypertensive diseases and drug treatment. This review summarizes the use of geriatric antihypertensive drugs and the often-preferred thiazidegazoles, as well as recent clinical trials of Verapamil and Alprenolol. First, the characteristics of senile hypertension According to the survey population incidence of hypertension, often with increasing age (but the indigenous Indians of Brazil, blood pressure does not increase with age, may be related to the family salt low). Sleigh seven that the elderly aortic plaque gradually formed and extended to the carotid sinus, followed by plastic yuan fiber instead, so that baroreceptor sensitivity decreased, leading to reduced vagal tone, sympathetic