患者,男性,48岁。因全身骨痛6年余,于1991年9月17日入院。6年前,患者无明确诱因感胸部、腰背部、双下肢疼痛,活动时加重。无游走性,局部无红肿,疼痛与气候变化无关。曾在多家医院求治,诊断为风湿性、类风湿性关节炎,骨关节炎,椎间盘突出等疾病。经理疗、硒部封闭、针灸、中药及抗风湿药治疗无效,全身骨痛症状逐年加重,不能坚持工作,走路需扶杖。近2月来,骨痛症状进一步加重,卧床不 Patient, male, 48 years old. Due to systemic pain more than 6 years, in September 17, 1991 admission. Six years ago, the patient had no specific incentive to feel the chest, lower back, lower extremity pain and increased activity. No migration, no local swelling, pain and climate change has nothing to do. In many hospitals for treatment, diagnosed as rheumatic, rheumatoid arthritis, osteoarthritis, disc herniation and other diseases. Manager treatment, selenium closed, acupuncture, traditional Chinese medicine and anti-rheumatic drugs ineffective, systemic bone pain increased year by year, can not adhere to work, walking stick. Nearly two months, the symptoms of bone pain worsened, bedridden