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目的 探讨提高接触粉尘工人体内抗超氧阴离子 (O-·2 )能力的方法 ,为寻找尘肺早期诊断的辅助指标及开壁治疗新途径提供依据。方法 检测接尘作业工人血液中超氧化物歧化酶 (SOD)及微量元素 (Cu、Zn、Mn)的含量 ,并对SOD含量下降工人进行治疗观察。结果 检测结果表明 ,接触碳素粉尘及碳黑粉尘工人血液中微量元素铜锌含量有不同程度下降 ,其中锌含量下降较明显 ;接尘工人血液中SOD含量下降 ,其下降幅度与接尘工龄相关不明显 ;接尘工人血液中SOD含量下降者经治疗后有明显提高 (2 4 2 %～ 5 3 3 % )。结论 接尘工人经用微量元素及清除自由基的药物治疗后 ,SOD含量有明显提高 ,为此 ,建议定期给接尘工人补充微量元素 (Cu、Zn)及维生素C、E ,提高他们抗超氧阴离子功能
Objective To explore ways to improve the ability of anti-superoxide anion (O-2) in contact with dust workers, and to provide evidences for finding the auxiliary index for early diagnosis of pneumoconiosis and new ways of opening the wall. Methods The levels of superoxide dismutase (SOD) and trace elements (Cu, Zn, Mn) in the blood of workers exposed to dust were detected and the workers with decreased SOD content were observed. Results The results showed that the levels of trace elements copper and zinc in the blood of workers exposed to carbon dust and carbon black dust decreased to some extent, and the zinc content decreased more obviously. The SOD level in the blood of workers exposed to dust decreased, Not obvious; dust workers exposed to the decline of SOD in blood after treatment was significantly improved (24% to 533%). Conclusion The dust content of workers exposed to trace elements and free radical scavenging drugs after treatment significantly increased SOD content, therefore, it is recommended to regularly add dust workers supplement trace elements (Cu, Zn) and vitamins C, E, to enhance their anti-super Oxygen anion function