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为探讨尿激酶对急性心肌梗塞患者心电图ＱＴ离散度（ＱＴｄ）的影响。分析６２例急性心肌梗塞病人，并以５０例正常人作对照。结果显示，心肌梗塞组的ＱＴｄ明显高于对照组（４４．５１±２９．７５ｍｓ比６０．７０±３２．５７ｍｓ，Ｐ＜０．０１）。治疗后，溶栓组ＱＴｃｄ明显低于非溶栓组（３８．１５±２１．６７ｍｓ比５７．６７±３１．８１ｍｓ，Ｐ＜０．０１）；再通组明显低于未通组（３２．３７±１８．９８ｍｓ比４９．７１±２３．１２ｍｓ，Ｐ＜０．０５）；溶栓组发病后第１ｍ内死亡率和恶性心律失常发生率皆明显低于非溶栓组（６．６７％比１２．５０％，６．６７％比１５．６３％，Ｐ＜０．０１）。上述结果提示，心肌梗塞病人的ＱＴｃｄ明显高于正常人；尿激酶能明显缩短心肌梗塞病人的ＱＴｃｄ，减少心肌梗塞病人的死亡率
To investigate the effect of urokinase on QTd in patients with acute myocardial infarction. Analysis of 62 cases of acute myocardial infarction patients, and 50 normal controls. The results showed that QTd in myocardial infarction group was significantly higher than that in control group (44.51 ± 29.75ms vs. 60.70 ± 32.57ms, P <0.01). After treatment, QTcd in thrombolytic group was significantly lower than that in non-thrombolytic group (38.15 ± 21.67 ms vs. 57.67 ± 31.81 ms, P <0.01); 37 ± 18.98ms vs 49.71 ± 23.12ms, P <0.05). The incidences of death and malignant arrhythmia within 1m after thrombolysis were significantly lower than those without thrombolysis (6.67% Than 12.50%, 6.67% vs 15.63%, P <0.01). The above results suggest that patients with myocardial infarction QTcd was significantly higher than normal; urokinase can significantly shorten the myocardial infarction patients QTcd, reduce myocardial infarction patients mortality