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应用神经行为学评估、脑梗死容积测量和 Westernblot分析 ,探讨研究阿魏酸钠 (SF)的神经保护作用及其对局灶性脑缺血损伤时突轴后致密物质 - 95 (PSD- 95 )活性的影响 ,证实 SF明显改善再灌注 2 4 h神经功能缺陷和减少脑梗死容积 ,显著增强再灌注后 PSD- 95表达 ,表明 SF可能通过加强PSD- 95活性来改善缺血性损伤
Neurobehavioral assessment, cerebral infarct volume measurement, and Western blot analysis were used to investigate the neuroprotective effect of sodium ferulate (SF) and its effect on the post-scleral densitometric substance-95 (PSD-95) during focal cerebral ischemic injury. The effect of activity confirmed that SF significantly improved neurological deficits and decreased cerebral infarct volume 24 hours after reperfusion, and significantly increased PSD-95 expression after reperfusion, suggesting that SF may improve ischemic injury by enhancing PSD-95 activity.