由于老年人对许多药物的反应与青壮年人不同,较易发生药物的不良副作用,有时甚为严重,所以对老年人如何安全用药,是很值得临床重视。尤其对老年人生理学改变与药物动力学的关系,以及药物性能等有关因素应予以注意。一、与年龄有关的生理学改变和药物动力学的关系: Because older people are different from young people in their reactions to many drugs, they are more likely to have adverse side effects and are sometimes more serious. Therefore, it is worthy of clinical attention to how to safely administer drugs to the elderly. In particular, physiological changes in the elderly and the relationship between pharmacokinetics, and drug performance and other related factors should be noted. First, age-related physiological changes and pharmacokinetics of the relationship: