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在应用抗生素而伴发的腹泻与结肠炎(AAD/AAC)中,由难辨梭状芽胞杆菌(Clostridium difficile)引起者约占五分之一。自1978年以来,斯德哥尔摩国家细菌实验室开展了难辨梭状芽胞杆菌(以下简称难辨梭菌)的诊断,并接受瑞典各地的粪便标本。本文概述难辨梭菌结肠炎(CDE)的现况和诊断过程。难辨梭菌是引起伪膜性结肠炎(PMC)的主要原因(70～95%),并与20%的AAD病例有关。由于有时难以对大量腹泻病人施行内窥镜检查以及结肠损害位于内窥镜检查不到的部位,因此经内窥镜检查证实结肠损害受到限制。多数严重的CDE为伪膜性类
In the application of antibiotics and associated diarrhea and colitis (AAD / AAC), caused by Clostridium difficile (Clostridium difficile) accounted for about one-fifth. Since 1978, the Stockholm National Bacteriological Laboratory has conducted a diagnosis of Clostridium difficile (Clostridium difficile) and received stool specimens from all over Sweden. This article provides an overview of the status and diagnosis of C. difficile colitis (CDE). Clostridium difficile is the leading cause of pseudomembranous colitis (PMC) (70-95%) and is associated with 20% of AAD cases. Due to the sometimes difficult to endoscopic examination of a large number of diarrhea patients and colon damage located in the endoscopic undetectable site, so endoscopically confirmed colon damage is limited. The most serious CDE is pseudomembranous