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一、PCO的病理生理据分析已确诊的100例PCO,大多数可从病史上与其他原因引起的长期不排卵症相鉴别。(1)初潮的平均年龄(12.3岁)和正常人群(12.9岁)相近,个别病例表现为原发闭经。(2)初潮后持久性月经不规则。(3)初潮前后已有临床上可识别的多毛(只有父母能提供可靠的病史)。(4)初潮前患者在同伴中已被视为过胖。因此,病史提示在青春期前,在下丘脑-垂体-卵巢系统最后确立周期性之前,已发生内分泌紊乱。 PCO特有的相当严重的男性毛发型往往是雄激素(A)增多的反映,几乎血液中
First, the pathophysiology of PCO According to the analysis of 100 cases of PCO have been diagnosed, most of them can be distinguished from other causes of chronic azoospermia in the history. (1) The average age of menarche (12.3 years) is similar to that of the normal population (12.9 years). Some cases showed primary amenorrhea. (2) Irregular menstruation after menarche. (3) Clinically identifiable hirsutum before and after menarche (only parents can provide a reliable medical history). (4) The patient has been considered obese in the companion before menarche. Therefore, medical history suggests that endocrine disorders have occurred before puberty and before the hypothalamic-pituitary-ovarian system is finally established. The PCO-specific rather severe male hair type is often a reflection of increased androgens (A), almost in the blood