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目的:为探讨我市上消化道疾病幽门螺杆菌(Helicobacter pylori,Hp)感染情况及影响因素。方法:对1 932人进行胃镜检查和活检,作尿素酶和Warthy-starry银染色。结果:1 932例病人中,Hp感染率为67.18%,其中胃癌为92.06%,十二指肠球部溃疡为80.40%,胃溃疡为75.70%,萎缩性胃炎为69.85%,浅表性胃炎为51.27%;农村Hp感染率为73.39%,城区为54.96%;41～50岁组为Hp感染高峰。结论:随消化道疾病加重,Hp感染升高。水质污染和居住拥挤,卫生条件差是Hp感染的主要原因之一。对Hp感染的预防和根除,可作为胃癌的一级预防措施。
Objective: To investigate the prevalence and influencing factors of Helicobacter pylori (Hp) infection in Shanghai upper gastrointestinal diseases. Methods: Gastroscopy and biopsy were performed on 1 932 persons for urease and Warthy-starry silver staining. Results: Among 1 932 patients, the infection rate of Hp was 67.18%, of which the gastric cancer was 92.06%, the duodenal ulcer was 80.40%, the gastric ulcer was 75.70%, the atrophic gastritis was 69.85%, the superficial gastritis was 51.27%. The infection rate of Hp in rural areas was 73.39%, and the urban area was 54.96%. The peak of Hp infection occurred in 41 ~ 50 years old group. Conclusion: Hp infection increases with the increase of digestive diseases. Water pollution and overcrowding, poor hygiene is one of the main causes of Hp infection. Prevention and eradication of Hp infection can be used as a primary preventive measure for gastric cancer.