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视黄酸(RA)可阻断化学诱癌剂诱发表皮、乳腺和膀胱等上皮类肿瘤,但RA是否可以使已恶变的肝癌细胞向良性方向逆转,国内外尚未见报道我们以肝癌较特异的癌胚蛋白——甲胎蛋白(AFP)及分化性蛋白——白蛋白(Alb)为指标,用10μmol/L RA处理(实验组)8MMC-7721入肝癌细胞株,初步发现明显抑制肝癌细胞的对数生长,在RA加入后第二天,实验组的细胞数为对照组的64％,第五天,
Retinoic acid (RA) can block epithelioid tumors such as skin, breast, and bladder induced by chemical carcinogens, but whether RA can reverse malignant hepatoma cells in a benign direction has not been reported at home and abroad. Oncofetal protein - alpha fetoprotein (AFP) and differentiated protein - albumin (Alb) as indicators, treated with 10μmol/L RA (experimental group) 8MMC-7721 into hepatocellular carcinoma cell line, initially found to significantly inhibit the liver cancer cells For logarithmic growth, the number of cells in the experimental group was 64% of the control group on the second day after RA was added. On the fifth day,