掌跖角化牙周破坏综合症是以快速进展的重度牙周组织破坏和掌跖角化为主要临床表现的常染色体隐性遗传性疾病,发病年龄早,常导致乳恒牙早失。本文报道1例掌跖角化牙周破坏综合征病例。 Palmoplantar periodontal destruction syndrome is a rapidly evolving severe periodontal tissue destruction and palmoplantar keratosis as the main clinical manifestations of autosomal recessive genetic disease, early onset, often lead to early loss of primary and permanent. This article reports a case of palmoplantar keratosis syndrome.