尽管喹诺酮类抗菌药在治疗多种细菌感染中得到了广泛应用,但其不合理使用导致的细菌(尤其是肺炎链球菌和流感嗜血杆菌)耐药性已日渐成为严重的临床问题。研究显示,大多数耐甲氧西林的金葡菌(MRSA)对现有的喹诺酮类药物均有耐药性,故新型强效的喹诺酮类抗菌药的研发从未中止。宝 Although quinolone antibacterials are widely used in the treatment of many bacterial infections, the resistance of bacteria (especially S. pneumoniae and H. influenzae) caused by their improper use has increasingly become a serious clinical problem. Studies show that most methicillin-resistant Staphylococcus aureus (MRSA) are resistant to existing quinolones, so the development of a new potent quinolone antibacterial has never stopped. treasure