1973年 Bishop 等用电子显微镜对患急性非细菌性胃肠炎病儿的十二指肠粘膜作活体组织检查,发现其上皮细胞内含有人类轮状病毒(HRV)。近十年中,国内外研究已证实,轮状病毒是引起小儿秋冬季腹泻的重要病原。1982年冬季,我们对南充地区流行的婴幼儿急性胃肠炎进行了临床观察,收集了部分患儿粪便在四 In 1973, Bishop et al examined the duodenal mucosa of children with acute non-bacterial gastroenteritis by electron microscopy and found that human epithelial cells contained human rotavirus (HRV). In recent ten years, domestic and foreign studies have confirmed that rotavirus is an important pathogen causing children’s diarrhea in autumn and winter. In the winter of 1982, we conducted a clinical observation on the acute gastroenteritis in infants and young children in Nanchong area,