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叶绿酸铜钠盐系以蚕粪为原料,经加工提制而得的叶绿素的衍化物。该盐曾被作成多种制剂用于治疗肝炎、胃十二指肠溃疡、急性胰腺炎、慢性肾炎、血液病及放射病和外用治疗创伤等,均有一定效果。济南东风制药厂以叶绿酸铜钠盐为主药作成乳膏剂(定名“绿宝乳膏”)治疗冻疮,经初步临床观察,其显效及有效率达97.58%。为了对叶绿酸铜钠盐及其乳膏的药理效应和毒性作些必要了解,我们进行了部分试验观察,现将结果报告如下:
Copper sodium chlorophyllin is a derivative of chlorophyll derived from silkworm excrement as raw material. The salt has been used as a variety of preparations for the treatment of hepatitis, gastroduodenal ulcer, acute pancreatitis, chronic nephritis, hematological diseases and radiation sickness and external treatment of trauma, have a certain effect. Jinan Dongfeng Pharmaceutical Co., Ltd. uses copper chlorophyllin as the main drug to make cream (named “Lubao Cream”) to treat frostbite. After preliminary clinical observation, the effective and effective rate is 97.58%. In order to make some necessary understanding of the pharmacological effects and toxicity of copper chlorophyllinate and its cream, we conducted some experimental observations and now report the results as follows: