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目的观察氯胺酮联合丙泊酚在小儿麻醉中的应用效果。方法选取医院收治的手术患儿64例为研究对象,随机分为观察组和对照组,每组32例。对照组采用氯胺酮麻醉,观察组采用氯胺酮联合丙泊酚麻醉。观察2组麻醉效果、生命体征情况、苏醒时间与不良反应发生情况。结果观察组麻醉显效率为71.9%,高于对照组的50.0%(P<0.05);麻醉中,观察组心率、血压、呼吸频率、血氧饱和度数值与麻醉前比较(P<0.05)。观察组麻醉苏醒时间为(19.5±5.1)min,短于对照组的(40.5±10.3)min(P<0.05);观察组不良反应发生率为12.5%,低于对照组的28.1%(P<0.05)。结论氯胺酮联合丙泊酚在小儿麻醉中的应用效果显著,值得临床推广应用。
Objective To observe the effect of ketamine combined with propofol in pediatric anesthesia. Methods Totally 64 children undergoing surgery were selected as study subjects and randomly divided into observation group and control group, with 32 cases in each group. The control group was anesthetized with ketamine, and the observation group was anesthetized with ketamine and propofol. The effects of anesthesia, vital signs, recovery time and adverse reactions in the two groups were observed. Results The effective rate of anesthesia in the observation group was 71.9%, higher than that in the control group (P <0.05). The values of heart rate, blood pressure, respiration rate and oxygen saturation in the observation group were significantly lower than those before the anesthesia (P <0.05). The anesthesia recovery time in the observation group was (19.5 ± 5.1) min, shorter than that in the control group (40.5 ± 10.3) min (P <0.05). The incidence of adverse reactions in the observation group was 12.5%, which was lower than that in the control group (28.1%, P < 0.05). Conclusion Ketamine combined with propofol has a significant effect in pediatric anesthesia and is worthy of clinical application.