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目的:探讨复方苦参注射液治疗癌症患者癌性疼痛的疗效。方法:将本院收治的晚期恶性肿瘤患者90例按随机数字表法分为两组,观察组45例给予复方苦参注射液静脉点滴1次/日,连用28天为1疗程,联合吗啡缓释片治疗。对照组45例单用吗啡片镇痛治疗,比较两组患者疼痛缓解的程度。结果:治疗后,两组患者的疼痛评分均降低,且观察组患者低于对照组,两组间的差异具有统计学意义(P<0.05);观察组和对照组患者疼痛缓解的有效率分别为68.89%和57.78%,观察组患者疼痛缓解的有效率显著高于对照组,差异具有统计学意义(P<0.05);观察组患者的生活质量评分高于对照组,差异具有统计学意义(P<0.05)。结论:复方苦参注射液治疗晚期癌症疼痛安全有效,能明显改善患者的生活质量。
Objective: To investigate the curative effect of compound Kushen injection on cancer patients with cancer pain. Methods: Ninety patients with advanced malignant tumors admitted to our hospital were divided into two groups according to random number table. The observation group received intravenous drip of Compound Kushen Injection once a day for 28 days, Release treatment. Control group, 45 cases of morphine alone analgesic treatment, the two groups were compared the extent of pain relief. Results: After treatment, the scores of pain in both groups were decreased, and the patients in the observation group were lower than those in the control group, the differences between the two groups were statistically significant (P <0.05); the pain relief rates in the observation group and the control group were respectively (68.89% vs 57.78%). The effective rate of relieving pain in observation group was significantly higher than that of control group (P <0.05), and the quality of life score of observation group was higher than that of control group (the difference was statistically significant P <0.05). Conclusion: Compound Kushen injection is safe and effective in the treatment of advanced cancer pain, and can significantly improve the quality of life of patients.