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【目的】了解宁波市区完成基础免疫儿童乙肝抗体水平。【方法】采用随机整群抽样的方法抽取宁波市江东区进行过三剂次乙肝基础免疫的466名入托入园儿童进行HBsAg和抗-HBs水平检测。【结果】未检测出乙肝病毒表面抗原阳性儿童,乙肝高抗体检出率为30.69%;1.5～2岁组、3岁和4岁以上组儿童高抗体检出率分别为35.42%、29.24%和15.79%;接种时间在出生后1个月内和1个月后的儿童高抗体检出率分别为27.25%和55.56%。【结论】入托入园儿童乙肝高抗体检出率较低,且随年龄的增加而降低,建议对低抗体或未检出抗体的健康儿童进行乙肝加强免疫。
【Objective】 To understand the level of hepatitis B antibody in basic immune children in Ningbo. 【Method】 A total of 466 nursery admission children undergoing three hepatitis B immunizations in Jiangdong District of Ningbo City were collected for the detection of HBsAg and anti-HBs using random cluster sampling method. 【Results】 The detection rate of HBeAg was 30.69% in children without HBsAg positive. The detection rates of high antibody in children aged 1.5-2 years, 3 years and above were 35.42% and 29.24%, respectively 15.79%. The detection rate of high antibody in children vaccinated within 1 month and 1 month after birth was 27.25% and 55.56% respectively. 【Conclusion】 The detection rate of HBsAg in children admitted to hospital is low and decreases with age. It is suggested that hepatitis B be boosted in healthy children with or without antibodies.