“碱C”是从雷公藤根(去皮)提取得到的一种单体,呈无色结晶粉末,焙点167～169℃。药理研究表明“碱C”对次溶血素反应为指标的体液免疫具有明显的抑制作用。80mg/kg对溶血素形成的抑制作用与环磷酰胺10mg/kg的作用相似,最大溶血稀释度下降1:256。雷公藤“碱C”对移植物抗宿液主反应(GVH)为指标的细胞免疫。当剂量呈为80mg/kg时对脾指数虽有降低,但抑 “Alkaline C” is a monomer extracted from the root (debarked) of Tripterygium wilfordii as a colorless crystalline powder with a baking point of 167-169°C. Pharmacological studies have shown that “alkaline C” has a significant inhibitory effect on the humoral immunity as an indicator of the hemolysin response. The inhibition of hemolysin formation by 80 mg/kg was similar to that of cyclophosphamide 10 mg/kg, and the maximum hemolytic dilution decreased by 1:256. Tripterygium wilfordii “base C” is an anti-host liquid host response (GVH) as an indicator of cellular immunity. When the dose is 80 mg/kg, although the spleen index decreases,