外周性原始神经外胚叶肿瘤(peripheral primitive neuroectodermal tumor,pPNET)是一种比较少见的软组织肿瘤,多见于儿童和年轻人,发生在鼻腔鼻窦者以上颌窦和鼻前庭为多见。现将我科收治的1例有鼻咽癌病史的蝶窦pPNET的病例报告如下。患者,女,46岁,12年前因回吸涕中带血取鼻咽部活检诊断为鼻咽癌,经系统放疗后,症状消失。半月前因发现回吸涕中带血来我院就诊,查体:右侧鼻黏膜稍充血,双侧鼻咽部未见明显异常。做鼻窦CT见右上颌窦内囊肿样占位,直径约3 cm;左蝶窦及相邻的后组筛窦内低密度占位(图1),双侧鼻腔鼻窦各骨质均正常,双侧咽鼓管、圆枕及咽隐窝未见明显异常。入院后查血常规、肝肾功、血沉、血清学均正常,完善术前检查 Peripheral primitive neuroectodermal tumor (pPNET) is a relatively rare soft tissue tumor, more common in children and young people, occurs in the nasal sinus are more common in the maxillary sinus and nasal vestibule. A case of nasopharyngeal carcinoma of the sphenoid sinus pPNET is now reported in our department as follows. The patient, female, 46 years old, diagnosed nasopharyngeal carcinoma with nasopharyngeal biopsy with resorption of tears in 12 years ago. After systemic radiotherapy, the symptoms disappeared. Half a month ago found back to the tears in the blood to our hospital, physical examination: a little congestion of the right nasal mucosa, bilateral nasopharyngeal no obvious abnormalities. Do sinus CT see the right maxillary sinus cyst-like occupancy, diameter of about 3 cm; left sphenoid sinus and adjacent posterior group of ethmoid low-density space (Figure 1), bilateral nasal sinus are normal bone, double Side eustachian tube, occipital and pharyngeal recess no significant abnormalities. Check the blood routine after admission, liver and kidney function, ESR, serology are normal, perfect preoperative examination