Important parameters used in safety evaluation of HLW disposal repository could be provided through migration study of key nuclides under the simulated disposal conditions which is one of the key contents of deep geological disposal research of HLW.Efforts are focused on solubility determination of neptunium and plutonium in simulated disposal conditions,diffusion behavior of technetium in decimeter level of Important parameters used in safety evaluation of HLW disposal repository could be provided through migration study of key nuclides under the simulated disposal conditions which is one of the key contents of deep geological disposal research of HLW. Efforts are focused on solubility determination of neptunium and plutonium in simulated disposal conditions, diffusion behavior of technetium in decimeter level of