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索他洛尔(sotalol)是一个兼有Ⅱ和Ⅲ类特征的抗心律失常药。最初在欧洲它是用作抗高血压的β阻滞剂。70年代初期发现它能延长高体心脏组织的动作电位时程,10年后又在人体得到证实。本品首先在欧洲、继在美国被用于治疗威胁生命的定性心律失常。1基本药动学特征1.1吸收和生?
Sotalol is an antiarrhythmic drug that combines both Type II and Type III features. It was originally used as an anti-hypertensive beta blocker in Europe. It was found in the early 1970s that it prolongs the action potential duration of high body heart tissue and is confirmed in the human body 10 years later. This product first in Europe, following the United States was used to treat life-threatening qualitative arrhythmia. 1 Basic pharmacokinetic characteristics 1.1 Absorption and Health?