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用CTN 1V株生产的精制Vero细胞狂犬病疫苗腹腔免疫小鼠后 ,再用狂犬病毒街毒株SBD0 7脑内和肌肉攻击 ,结果表明稀释 5倍疫苗的保护率分别为 88 9%和 90 % ,且 5倍稀释疫苗的保护效果与原苗相当 ,此研究证明CTN 1V株能用来作为疫苗的生产毒株。
The mice were immunized intraperitoneally with purified Vero cell rabies vaccine produced by CTN 1V strain and then challenged with rabies virus Streptococcus pneumoniae strain SBD0 7 in brain and muscle respectively. The results showed that the protective rates of vaccine diluted 5 times were 88 9% and 90% And 5-fold dilution of the protective effect of vaccines and seedlings equivalent to this study shows that CTN 1V strain can be used as vaccine production strain.