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作者报告一例病窦综合征用乙胺碘呋酮治疗,治疗前肺部正常,患者否认有劳力性气短史,用药后病窦症状很快消失。六周后发生劳力性气短,且进行性加重,胸部X线片两肺上有多处小片状阴影,肺科医生肺活检考虑肺水肿,但对利尿剂缺乏反应,停用乙胺碘呋酮后气短好转,用强的松每日60mg,很快运动耐受性改善,肺野逐渐清晰,再未出现气短。肺泡炎的发病机理尚未弄清,这一例原因可能是对乙胺碘呋酮高度过敏反应。其它的可能性有:类风湿性间质性肺炎,胶原性血管疾患,或自身免疫疾
The authors report a case of sick sinus syndrome with amiodarone treatment, before treatment of normal lungs, patients denied a history of labor with shortness of breath, sick sinus symptoms disappeared quickly after treatment. After six weeks of labor-induced shortness of breath, and the progressive increase in chest X-ray films on both sides of the lung there are many small pieces of lung biopsy pulmonary disease to consider pulmonary edema, but the lack of response to diuretics, discontinuation of amiodarone Ketone improved after a short, with prednisone daily 60mg, improved exercise tolerance, lung field gradually clear, then no shortness of breath. The pathogenesis of alveolitis has not yet been clarified, which may be due to a high degree of allergic reactions to amiodarone. Other possibilities are: rheumatoid interstitial pneumonia, collagen vascular disease, or autoimmune disease