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由于直接与结肠粘膜接触的微生物与粪便菌丛共存,所以健康者或炎症性肠病患者中肠道细菌与肠道粘膜损伤之间的关系很难被证实。本文通过联合应用多种检测方法,探讨了炎症性肠病患者肠道细菌与肠道粘膜损伤的关系。 方法:305例慢性炎症性肠病患者(28例自限性结肠炎、104例不确定性结肠炎、119例溃疡性结肠炎和54例克罗恩病)和40例经结肠镜检查未发现炎症的对照者,在结肠镜检查时分别在回肠、升结肠和乙状结肠处取活检标本,并将其
The relationship between intestinal bacteria and intestinal mucosal damage in healthy or inflammatory bowel disease patients is difficult to confirm due to the coexistence of microorganisms in direct contact with colonic mucosa with fecal flora. In this paper, a combination of a variety of detection methods to explore the relationship between intestinal bacteria and intestinal mucosal injury in patients with inflammatory bowel disease. METHODS: A total of 305 patients with chronic inflammatory bowel disease (28 self-limiting colitis, 104 indeterminate colitis, 119 ulcerative colitis and 54 Crohn’s disease) and 40 colonoscopy were not found Inflammatory controls, colonoscopy in the ileum, ascending colon and sigmoid colon biopsy specimens, and its