尿道下裂是男性小儿泌尿生殖系统最常见的先天性畸形之一。据统计,尿道下裂在我国活产婴儿中的发病率约为0·4%。虽然世界各国报道的尿道下裂发病率存在较大差异,但总体上均呈现逐年增加的趋势。目前,尿道下裂的病因仍不明确,其发病可能与多种物质间的协同作用或相加作用有关, Hypospadias is one of the most common congenital malformations of the male genitourinary system in children. According to statistics, the incidence of hypospadias in live births in China is about 0.4%. Although the incidence of hypospadias reported in various countries in the world there is a big difference, but overall showed a trend of increasing year by year. At present, the cause of hypospadias is still not clear, its incidence may be related to the synergistic effect or additive effect of many substances,