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目的探讨馒头餐试验是否可代替胰升糖素C肽刺激试验以评价胰岛B细胞功能。方法112例糖尿病病人连续2天分别进行馒头餐试验和胰升糖素C肽刺激试验。结果馒头餐后1、2、3小时血C肽与胰升精素试验6分钟C肽水平呈明显正相关（2型糖尿病组的相关系数分别为0．718、0．710、0．758，P均＜O．001；1型糖尿病组的相关系数分别为0．96、0．93、0．89，P＜0．001）。结论对进行胰升糖素C肽刺激试验有禁忌证的病人，可用馒头餐试验来了解胰岛B细胞储备功能。
Objective To investigate whether steamed bread meal test can replace glucagon C-peptide stimulation test to evaluate islet B cell function. Methods One hundred and twelve patients with diabetes mellitus were subjected to steamed bread meal test and glucagon C-peptide stimulation test for two consecutive days. Results 1, 2 and 3 hours postprandial blood C peptide and pancreatic ascending test 6-minute C-peptide levels showed a significant positive correlation (type 2 diabetes, the correlation coefficients were 0.718,0.710,0.758, P <0.001; the correlation coefficient of type 1 diabetes group was 0.96, 0.93, 0.89 respectively, P <0.001). Conclusions Patients with contraindications to the stimulation of glucagon C-peptide may use the steamed bread test to understand the islet B-cell reserve function.