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无论T1DM还是T2DM,β细胞功能受损是血糖升高的决定因素。迄今为止,还未发现1例只有胰岛素抵抗(1R)而无β细胞功能受损而血糖升高的病例。因此,人们对β细胞功能受损的病因、机理、表现和临床评价以及治疗方法的选择作了大量研究。本文对T2DM患者β细胞功能受损的表现、评价作一浅拆。1定义β细胞功能定义还不十分明确。狭义的定义是指β细胞在葡萄糖的刺激下以维持血糖水平稳定的功能。
Whether T1DM or T2DM, β-cell dysfunction is a determinant of elevated blood glucose. To date, no single case of insulin resistance (1R) has been found without impaired beta-cell function and hyperglycemia. Therefore, a great deal of researches have been made on the etiology, mechanism, manifestation and clinical evaluation of β-cell dysfunction and the choice of treatment methods. This article on T2DM patients with β-cell dysfunction performance, evaluation of a shallow demolition. 1 Definition of β-cell function is still not very clear. The narrow definition refers to the beta cells in glucose stimulation to maintain the stability of blood glucose levels.