目的:观察肺癌患者化疗期间合并下呼吸道感染情况,从而为下一步治疗提供有效的预防措施。方法:经病理学或细胞学证实的436例肺癌患者给予铂类为主的化疗,大部分接受4~6个疗程,个别接受6个以上疗程。结果:全组肺癌患者共436例,其中合并下呼吸道感染123例,感染发生率为24.2%。且症状不典型。X线特征为小片状或大片浸润样阴影阻塞性肺炎和肺不张。结论:肺癌患者化疗期间合并下呼吸道感染几率高,且与化疗次数相关联,故在肺癌化疗期间应及早加强免疫支持治疗。 Objective: To observe the patients with lung cancer complicated by lower respiratory tract infection during chemotherapy, so as to provide effective preventive measures for the next step of treatment. Methods: 436 cases of lung cancer confirmed by pathology or cytology were treated with platinum-based chemotherapy. Most received 4-6 cycles of treatment and received more than 6 cycles of treatment individually. Results: A total of 436 patients with lung cancer were included in the study. Among them, 123 cases were complicated with lower respiratory tract infection and the infection rate was 24.2%. And the symptoms are not typical. X-ray features of small pieces or large infiltration of shadow obstructive pneumonia and atelectasis. Conclusion: There is a high incidence of lung cancer complicated with lower respiratory tract infection during chemotherapy, which is associated with the frequency of chemotherapy. Therefore, it is necessary to strengthen the immune support as soon as possible during the chemotherapy of lung cancer.