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北豆根粗总碱、多酚羟基碱和非酚性总碱对小鼠巴豆油性耳廓水肿及大鼠角叉菜胶性足跖水肿均有明显的抑制作用。粗总碱和多酚羟基碱对大鼠巴豆油性肉芽囊肿的炎性渗出及囊壁增生也有抑制作用,非酚性总碱则否。粗总碱和多酚羟基碱对Freund’s完全佐剂诱发大鼠关节炎有明显抑制作用。多酚羟基碱能减少大鼠肾上腺中抗坏血酸的含量。
The crude total alkaloids, polyphenols hydroxyl bases and non-phenolic total alkaloids of Rhododendron fortunei have significant inhibitory effects on oily auricular edema in mice and carrageenan tinea edema in mice. Crude alkaloids and polyphenol hydroxyl bases also inhibited the inflammatory exudation and cyst wall hyperplasia of rat oily granulocysts in Croton, but non-phenolic total alkaloids did not. The crude total base and polyphenol hydroxy base have obvious inhibitory effects on Freund’s complete adjuvant-induced arthritis in rats. Polyphenol hydroxyl base can reduce the content of ascorbic acid in rat adrenal glands.