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目的观察善宁及清胰汤联合应用对急性胰腺炎的治疗作用。方法2002年10月~2005年12月我科收住急性胰腺炎患者84例,患者入院后随机分为两组:对照组40例,给予禁食、胃肠减压、抑酸、生长抑素(善宁)及支持对症治疗;治疗组44例,加用清胰汤,余治疗同对照组。观察两组患者腹部症状及体征的缓解情况,血、尿淀粉酶、血常规及肝功能等恢复情况,临床并发症、治愈率等。结果治疗组在患者症状、体征的缓解率,5d内血、尿淀粉酶恢复及减少并发症等方面均明显优于对照组。治疗组总有效率明显优于对照组。结论治疗组在急性胰腺炎早期无论腹部症状、体征的缓解,还是血、尿淀粉酶的恢复情况均显著优于对照组,并发症明显少于对照组,总有效率明显提高。
Objective To observe the therapeutic effect of the combined application of Shanning and Qingyi Decoction on acute pancreatitis. Methods From October 2002 to December 2005, 84 patients with acute pancreatitis were admitted in our department. The patients were randomly divided into two groups after admission: the control group of 40 cases, given fasting, gastrointestinal decompression, acid suppression, somatostatin (Shanning) and support symptomatic treatment; treatment group 44 cases, plus Qingyitang, Yu treatment with the control group. The relief of abdominal symptoms and signs, the recovery of blood and urine amylase, blood and liver function, clinical complications and cure rate were observed in the two groups. Results The treatment group was significantly better than the control group in alleviating symptoms and signs, recovering blood and urine amylase within 5 days, and reducing complications. The total effective rate of treatment group was significantly better than that of control group. Conclusion In the early stage of acute pancreatitis, the treatment group showed significantly better recovery than those in the control group, regardless of abdominal symptoms, signs, or blood and urine amylase. Complications were significantly less than those in the control group, and the total effective rate was significantly increased.