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目的:评价选择性支气管动脉灌注化疗问AI)和胸腔内灌注化疗(Pll)联合治疗晚期非小细胞肺癌(NSCDe)伴恶性胸腔积液(MPE)的疗效。材料和方法:30例病变局限于胸部的晚期NSCLC伴MPE患者。先经BAI治疗2-7天再行PLI。结果:肺部原发灶有效率86.7%,MPE有效率93.3%,6个月、1年、2年生存率分别为对.3%、63.3%、30%。结论:BAI和PLI联合治疗晚期NSCLC伴MPE安全有效,先用BAI,后用PLI,效果较好。
OBJECTIVE: To evaluate the efficacy of selective bronchial arterial infusion chemotherapy (AI) and intrapleural infusion chemotherapy (Pll) in the treatment of advanced non-small cell lung cancer (NSCDe) with malignant pleural effusion (MPE). Materials and Methods: Thirty patients with advanced NSCLC with MPE were confined to the chest. The PLI was first treated with BAI for 2-7 days. Results: The efficiency of primary foci of lung was 86.7%, and the effective rate of MPE was 93.3%. The survival rates of 6 months, 1 year, and 2 years were respectively correct. 3%, 63.3%, 30%. Conclusion: The combination of BAI and PLI is safe and effective in the treatment of advanced NSCLC with MPE. The first use of BAI followed by PLI has a good effect.