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目的观察胰岛素强化治疗对2型糖尿病合并冠心病心衰患者的影响。方法选取焦作市第四人民医院2009年1月至2012年6月住院治疗的2型糖尿病合并冠心病心衰患者107例,随机分为治疗组、对照组,治疗组给予胰岛素泵持续皮下注入门冬胰岛素,对照组给予精蛋白锌胰岛素30R皮下注入,观察患者血糖达标时间、糖化血红蛋白、血脂、左室射血分数的变化。结果治疗后血糖达标时间治疗组(5.20±1.38)d,对照组(8.14±1.47)d;糖化血红蛋白:治疗组(7.23±1.08)%,对照组(7.87±1.23)%;左室射血分数:治疗组(57.31±4.26)%,对照组(50.28±5.12)%。两组比较差异有统计学意义(P<0.05)。结论胰岛素强化治疗2型糖尿病合并冠心病心衰,血糖达标时间短,心功能改善明显。
Objective To observe the effect of intensive insulin therapy on type 2 diabetes mellitus patients with coronary heart disease. Methods A total of 107 patients with type 2 diabetes mellitus complicated with coronary heart disease and heart failure admitted to the Fourth People’s Hospital of Jiaozuo City from January 2009 to June 2012 were randomly divided into treatment group, control group and treatment group with continuous subcutaneous injection of insulin pump Insulin, the control group was given subcutaneous injection of protamine zinc insulin 30R, observation of patients with glycometabolism time, glycosylated hemoglobin, lipids, left ventricular ejection fraction changes. Results After treatment, the blood glucose reached the standard of treatment time (5.20 ± 1.38) d in the control group (8.14 ± 1.47) d, HbA1c (7.23 ± 1.08)% in the control group and 7.87 ± 1.23% in the control group : The treatment group (57.31 ± 4.26)%, the control group (50.28 ± 5.12)%. The difference between the two groups was statistically significant (P <0.05). Conclusion Insulin-intensified treatment of type 2 diabetes with coronary heart disease, blood glucose compliance time is short, cardiac function improved significantly.