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为进一步探讨冠心病的病因及防治措施,检测了50例正常人及50例冠心病患者的血小板功能。其中14例冠心病患者进行了经皮冠状动脉腔内成形术(PTCA),并观察了PTCA对血小板功能的影响。冠心病患者血小板聚集及粘附率均高于正常人。PTCA术后血小板聚集及粘附率均降低,与术前比较有非常显著性差异(P<0.01)。研究结果表明,冠状动脉狭窄程度与血小板聚集及粘附率有关。检测血小板聚集及粘附功能对冠心病的诊断及PTCA术后的疗效有重要作用。
To further explore the etiology and prevention and treatment of coronary heart disease, 50 normal subjects and 50 patients with coronary heart disease were tested for platelet function. Among them, 14 cases of coronary heart disease underwent percutaneous transluminal coronary angioplasty (PTCA), and observed the effect of PTCA on platelet function. Platelet aggregation and adhesion rate in patients with coronary heart disease were higher than normal. Platelet aggregation and adhesion rate after PTCA decreased, with significant difference compared with preoperative (P <0.01). The results show that the degree of coronary artery stenosis and platelet aggregation and adhesion rate. Detection of platelet aggregation and adhesion function of coronary heart disease diagnosis and efficacy of PTCA has an important role.