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目的对比鼻窦镜手术对慢性鼻-鼻窦炎(CRS)患者的临床疗效及对鼻黏液纤毛清除功能的影响。方法随机选取2014年10月至2016年5月76例慢性鼻-鼻窦炎患者,通过随机数表法分组,每组38例。研究组采用鼻窦镜手术,对照组采用传统手术。对比治疗前后两组临床症状(头痛、面部疼痛、鼻塞、嗅觉障碍、鼻分泌物)评分、鼻黏液纤毛清除功能(鼻黏液纤毛清除率、鼻黏液纤毛清除速度、糖精消除时间)变化情况,统计两组临床疗效。结果治疗前两组头痛、面部疼痛、鼻塞、嗅觉障碍、鼻分泌物评分对比差异未见统计学意义(P>0.05),治疗后研究组各指标评分低于对照组,差异有统计学意义(P<0.05);研究组总有效率(97.37%)高于对照组(78.95%),差异有统计学意义(P<0.05);治疗后研究组两组鼻黏液纤毛清除率、鼻黏液纤毛清除速度、糖精消除时间均优于对照组,差异有统计学意义(P<0.05)。结论采用鼻窦镜手术治疗慢性鼻-鼻窦炎效果显著,可改善患者临床症状,提高鼻黏液纤毛清除功能与治疗效果。
Objective To compare the clinical efficacy of sinusoscopic surgery in patients with chronic rhinosinusitis (CRS) and its effect on nasal mucociliary clearance. Methods A total of 76 patients with chronic rhinosinusitis from October 2014 to May 2016 were randomly selected and randomly divided into groups of 38 patients. The study group used sinus surgery, while the control group used traditional surgery. The changes of clinical symptoms (headache, facial pain, nasal obstruction, olfactory dysfunction and nasal secretions), changes of nasal mucociliary clearance (nasal mucociliary clearance, nasal mucociliary clearance and saccharin elimination time) before and after treatment were compared between the two groups. Statistics Two groups of clinical efficacy. Results There was no significant difference in headache, nasal obstruction, olfactory dysfunction and nasal secretion score between the two groups before treatment (P> 0.05). After treatment, the score of each index of the study group was lower than that of the control group (the difference was statistically significant P <0.05). The total effective rate (97.37%) in the study group was significantly higher than that in the control group (78.95%) (P <0.05). After treatment, the nasal mucociliary clearance rate, nasal mucociliary clearance Speed, saccharin elimination time are better than the control group, the difference was statistically significant (P <0.05). Conclusions Sinusoscopic surgery for chronic rhinosinusitis has significant effect, which can improve the clinical symptoms and improve the function and therapeutic effect of nasal mucociliary clearance.