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研究扶正化瘀方较肝丸改善肝功能、抑制肝纤维化的疗效。用软肝丸治疗肝炎肝硬化45例，另设对照组43冽，治疗前后观察症状、体征；肝功能检测；测定血清透明质酸（HA），Ⅲ型前胶原（PCⅢ）。结果：治疗组症状、体征的改变明显优于对照组（P＜0．05）肝功能明显改善。HA及PCⅢ分别由治前的398±196（μg/L）及342±6．25（μg/L）下降至治疗后的190±78（μg/L）及110．8±57．2（μg/L）（P＜0．01）。治疗组肝功能的改善及PCⅢ、HA的降低，明显优于对照组。结论：软肝丸治疗肝炎肝硬化三个月，肝功能明显改善，肝纤维化亦明显减轻。
Research Fuzhenghuayu than liver pills to improve liver function, inhibit the efficacy of liver fibrosis. Forty-five patients with cirrhosis of liver were treated with Ruan Gan Wan, and another 43 patients with control group were treated with Ruan Gan Wan. The symptoms and signs were observed before and after treatment. The serum levels of hyaluronic acid (HA) and procollagen Ⅲ (PC Ⅲ) were measured. Results: The changes of symptoms and signs in the treatment group were significantly better than those in the control group (P <0.05). The liver function improved significantly. HA and PCⅢ decreased from 398 ± 196 (342 μg / L) and 342 ± 6.25 (μg / L) to 190 ± 78 (μg / L) and 110.8 ± 57.2 /L)(P<0.01). The treatment group improved liver function and PC Ⅲ, HA decreased significantly better than the control group. Conclusion: Ruangan pill three months treatment of hepatitis cirrhosis, liver function improved significantly, liver fibrosis was also significantly reduced.