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目前已用于血吸虫病的各种免疫学诊断技术,都是以检出宿主体内对血吸虫抗原的特异性抗体为基础的,还不能单独用作流行病学调查个别病例确诊及考核防治效果的工具,而只能作为病原学诊断的补充。除了通过纯化抗原的使用和改进试验技术,以提高已有的各种方法的特异性和敏感性,增加其实用价值外,还需发展能从宿主体液中检出血吸虫特异性抗原的技术,使有可能提供证明体内有活虫存在及表明感染程度的血清学方法。本文就国外近年来有关血吸虫特异性循环抗原的研究作一简要的综述。【宿主循环血液内虫源特异性抗原的证明】
Currently, various immunological diagnostic techniques for schistosomiasis are based on the detection of specific antibodies against schistosome antigens in the host, and can not be used alone as a tool for epidemiological investigation on the diagnosis and prevention and treatment of individual cases , But only as a supplement to the etiological diagnosis. In addition to the use of purified antigens and improved testing techniques to enhance the specificity and sensitivity of various existing methods and to increase their practical value, there is a need to develop techniques that can detect schistosome-specific antigens from host fluids It is possible to provide serological methods that demonstrate the presence of live worms in the body and indicate the extent of infection. This review summarizes the recent studies on the specific circulating antigens of Schistosoma japonicum in foreign countries. [Host circulating blood-specific proof of insect-specific antigen]