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动脉粥样硬化症是一种危害人类健康的常见病。近年来国内报道有些中药在治疗冠心病方面取得了肯定的效果。袁家玑教授经验方—“冠心通络舒郁丸”(以下称本方),经我院临床多年应用,疗效显著。本文拟就本方对实验性动脉粥样硬化症的作用进行病理形态学观察。材料和方法一.动物模型的复制及分组:大耳白兔27只,性别不拘,体重2—3kg,经常规检疫,用本实验室基础饲料分笼饲养,稳定4周后,随机分为三组,即对照、服药和空白组。空白组每日仅服基础饲料。对照组加服造型剂(胆固醇、蛋黄粉和猪油,按间歇法服用)。服药组加服本方每日每只1丸,余同对照组。药物由贵阳中医学院一附院中药厂供给。
Atherosclerosis is a common disease that harms human health. In recent years, some Chinese medicines have reportedly achieved positive results in the treatment of coronary heart disease. Prof. Yuan Jiaxuan’s experience—“Guanxin Tongluo Shuyu Pill” (hereinafter referred to as “the party”) has been used clinically for many years in our hospital and has a significant effect. This article intends to observe the pathomorphological effects of this prescription on experimental atherosclerosis. Materials and Methods 1. Animal model reproduction and grouping: 27 big white rabbits, unrestrained gender, weighing 2-3 kg, routine quarantine, caged with the basic feed for this laboratory, stable for 4 weeks, randomly divided into three Groups, ie, controls, medications, and blank groups. The blank group only served the basic feed daily. The control group was given a styling agent (cholesterol, egg yolk powder, and lard, taken on a batch basis). The medication group took one pill per day for each side of the prescription, leaving more than the control group. The drug was supplied by the Chinese Academy of Traditional Chinese Medicine at the Guiyang College of Traditional Chinese Medicine.