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目的观察6-OHDA致大鼠发生PD对纹状体SG的影响,探讨PD鼠纹状体移植同种胎鼠中脑细胞和皮层细胞对纹状体SG的影响及其可能机制,观察纹状体移植不同胎鼠脑细胞对PD鼠旋转行为的改善作用·方法将46只6-OHDA致PD模型成功的成年雌Sprague-Daw ley鼠随机分成4组:6-OHDA致PD模型组(PD-
Objective To observe the effect of PD on striatum SG induced by 6-OHDA in rats and to explore the effect of brain cells and cortical cells in striatum on striatum SG and its possible mechanism To study the effect of different body weight of fetal rat brain cells on the rotational behavior of PD rats.Methods 46 adult female Sprague-Dawley rats induced by 6-OHDA induced PD model were randomly divided into 4 groups: 6-OHDA induced PD model group (PD-