原发性十二指肠癌占尸体解剖时发现的肿瘤中的0.019～0.5％,除去乏特氏壶腹部的癌肿后,十二指肠癌在所有小肠癌中占17～45％,在全胃肠道的恶性肿瘤中占0.35％左右。近时Spira指出,在广泛应用纤维内窥镜之后,十二指肠肿瘤已较以往有更多的发现。目前,十二指肠癌的病因仍不完全明了,它不可能是酸、碱或酶作用的结 Primary duodenal cancer accounts for 0.019 to 0.5% of the tumors found during autopsy. After removal of cancer in the ampulla of Vater, duodenal cancer accounts for 17 to 45% of all small intestine cancers. About 0.35% of the total gastrointestinal cancers account for about 0.35%. Spira pointed out that after extensive use of fiber endoscopes, duodenal tumors have seen more than ever before. At present, the cause of duodenal cancer is still not completely understood. It cannot be an acid, alkali or enzymatic knot.