气管支气管软化(TBM)是婴幼儿期气道阻塞的一个重要原因,但通常可随气道发育扩大而缓解。 气管支气管软化,可分为原发性与继发性两种。原发性TBM少见,是由于气管、支气管树软骨先天性软弱所致。原发性TBM可单独发生,也可并发其他先天性异常。本文研究发现TBM发病与几种遗传性颅面综合征及其他先天性异常有关。有报告TBM与某些遗传综合征如:Larsen’s综合征及多发性软骨炎有关。 继发性TBM常见,通常是由于患RDS的早产儿 Tracheal bronchoconstriction (TBM) is an important cause of airway obstruction in infancy, but it is usually relieved by the expansion of airway development. Tracheal bronchial softening can be divided into two primary and secondary. Primary TBM rare, due to tracheobronchial tree cartilage due to congenital weakness. Primary TBM can occur alone, but also with other congenital anomalies. This study found that the pathogenesis of TBM and several hereditary craniofacial syndrome and other congenital anomalies. There are reports of TBM and some genetic syndromes such as: Larsen’s syndrome and multiple chondritis. Secondary TBM is common, usually due to premature infants with RDS