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目的 :研究性激素与缺血性脑血管病的关系。方法 :采用放射免疫学方法 ,测定了 68例缺血性脑血管病患者血清性激素 :催乳素、雌二醇、孕酮、睾酮水平 ,并与 72例健康老年人进行比较。结果 :女性缺血性脑血管病患者血清中雌二醇含量 ( 16 12±3 5 7ng/l)明显低于对照组 ( 18 71± 3 41ng/l P <0 0 1)。结论 :缺血性脑血管病女性患者雌激素水平降低明显 ,考虑绝经期妇女缺血性脑血管病的发病与雌激素水平的降低可能有关。
Objective: To study the relationship between sex hormones and ischemic cerebrovascular disease. Methods: The levels of serum sex hormones including prolactin, estradiol, progesterone and testosterone in 68 patients with ischemic cerebrovascular disease were determined by radioimmunoassay and compared with 72 healthy controls. Results: Serum estradiol levels in female patients with ischemic cerebrovascular disease (16 12 ± 37 57 ng / l) were significantly lower than those in the control group (18 71 ± 41 1 ng / l P <0.01). Conclusion: Estrogen levels in female patients with ischemic cerebrovascular disease decreased significantly, and the incidence of ischemic cerebrovascular disease in menopausal women may be related to the decrease of estrogen levels.