论文部分内容阅读
目的调查分析哈尔滨一所大学4名同寝学生甲状腺疾病集中发生的原因。方法对该校包括4名同寝甲状腺疾病患者在内的98名学生和50名学校教工作为对象,对可能造成4名学生甲状腺疾病的病因包括放射线接触史、碘摄入情况、家族史、心理因素等进行问卷调查、甲状腺触诊和B超诊断、学校饮用水水碘测定、食堂盐碘和学生尿碘含量测定,从而分析该现象的成因。结果此次调查的148人共4人诊断为地方性甲状腺肿大,甲肿率为2.7%;B超检测有23人甲状腺表现异常(腺瘤、囊肿、结节等),B超异常率27.06%(23/85);总异常人数26人,总异常率为17.57%。对检查甲状腺异常的26人和甲状腺正常的122人问卷调查因素进行χ2检验,均无统计学意义,说明相关调查因素与此次甲状腺疾病的发病无关;8份水样的水碘值均小于10μg/L;8份盐样均为合格碘盐;148人的尿碘中位数为173.2μg/L,该校学生和教工的碘营养状况处于适宜状态。结论尚不能认为此次事件是由生活环境碘缺乏或碘过量所致,但甲状腺异常率较高,特别是出现甲状腺癌患者,此现象应引起关注。
Objective To investigate and analyze the causes of thyroid disease in four cohorts of a university in Harbin. Methods A total of 98 students and 50 faculty members of the school, including 4 patients with thyroid disease, were enrolled in this study. The causes of thyroid disease in 4 students including history of radiation exposure, iodine intake, family history, psychology Factors such as questionnaire survey, thyroid palpation and B-ultrasound, school drinking water iodine determination, canteen salt iodine and urinary iodine content of students to analyze the causes of the phenomenon. Results A total of 148 patients in this survey were diagnosed as endemic goiter with a goiter rate of 2.7%. Thyroid abnormalities (adenomas, cysts, nodules, etc.) were observed in 23 of the 23 hypertrophy patients. The abnormal rate of B-ultrasound was 27.06 % (23/85); the total number of anomalies was 26, with a total abnormal rate of 17.57%. There were no significant differences between the 26 surveyed thyroid abnormalities and the 122 normal thyroid survey questionnaires, which indicated that the relevant investigation factors were unrelated to the incidence of this thyroid disease. The water iodine values of 8 water samples were less than 10μg / L; 8 salt samples were qualified iodized salt; the median urinary iodine of 148 people was 173.2μg / L, the iodine nutritional status of students and faculty in this school was in a proper state. Conclusions It can not yet be considered that this incident is caused by iodine deficiency or iodine excess in the living environment, but there is a high rate of abnormality of the thyroid gland, especially in patients with thyroid cancer. This phenomenon should be of concern.