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目的探讨2型糖尿病糖化血红蛋白与血脂水平的相关性。方法将579例2型糖尿病患者依据HbA1c分组,分析HbA1c对血脂的影响,并进一步对血脂异常组做Logistic回归多因素分析。结果血糖控制差组的总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白(LDL)和极低密度脂蛋白(VLDL)显著高于血糖控制良好组(P<0.05),血糖控制良好组的高密度脂蛋白(HDL)显著高于血糖控制较差组(P<0.05),高TC组、高LDL组和低HDL组的糖化血红蛋白显著高于正常对照组(P<0.05)。结论 2型糖尿病患者的糖化血红蛋白与血脂存在明显的相关性。
Objective To investigate the relationship between type 2 diabetes mellitus and serum lipids. Methods According to the HbA1c grouping, 579 type 2 diabetic patients were divided into groups to analyze the influence of HbA1c on blood lipids. Logistic regression multivariate analysis was performed on dyslipidemia group. Results The total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL) and very low density lipoprotein (VLDL) in the poor glycemic control group were significantly higher than those in the control group with good glycemic control (P <0.05) The HDL of the good group was significantly higher than that of the poor control group (P <0.05). The HbA1c of the high TC group, the high LDL group and the low HDL group were significantly higher than those of the normal control group (P <0.05). Conclusions There is a clear correlation between HbA1c and blood lipid in type 2 diabetic patients.